Clinical trials

Pilot Study of Neoantigen Profiling in Patients with Melanoma Treated with PD-1 Blockade

This research study is designed to better understand the molecular determinants of response to immunotherapies including pembrolizumab and nivolumab. We hope to learn the relevance of tumor neoantigens in the recognition of cancer cells by the immune system. The ultimate goal is to rank and filter these neoantigens and correlate with response to immunotherapies.